Microrobotic platform for the image-guided endovascular intervention

Overview

A microrobotic platform for the image-guided endovascular intervention for treatments of vascular diseases. The microrobotic platform utilizes the nanorobots swarm and the magnetic actuation system for active drug delivery to a targeted region inside the vessels, delivering high dose of drugs to the region locally with lower overall required drug dosage.

Commercialisation opportunities

Exclusive licensing

Problem addressed

Endovascular interventions are essential for the treatment of various vascular diseases. However, they are often limited by the tethered design and size of the medical tools, making access to tiny and tortuous vessels time consuming or even impossible, causing complications or even death of the patients.

Innovation

Targeted drug delivery in tiny and tortuous vessels with high efficiency using microrobotic swarm
Enhanced thrombolysis rate by the chemical-mechanical interaction between the nanorobots and blood clot
Cleaning blood clot that can hardly be reached by conventional methods

Key impact

Potentially provide a new enabling technology for a more efficient treatment of thrombosis with reduced drug dosage and enhanced thrombolysis rate, minimizing the side effect of thrombolysis and widening the therapeutic time window.
Benefit millions of patients with different thrombosis diseases.
Pave the way towards the in vivo application of nanorobotics for different clinical uses

Award

IEEE ARM 2020 Toshio Fukuda Best Paper Award in Mechatronics
IEEE CASE 2020 Best Student Paper Award

Application

Endovascular intervention for thrombosis therapy
Treatment in tiny and tortuous vessels deep inside human body

Patent

2 US non-provisional Patent Filed US20210369373A1 US20210393356A1

Website

The Chinese University of Hong Kong (CUHK)

Founded in 1963, The Chinese University of Hong Kong (CUHK) is a forward-looking comprehensive research university with a global vision and a mission to combine tradition with modernity, and to bring together China and the West. CUHK teachers and students hail from all around the world. Four Nobel laureates are associated with the university, and it is the only tertiary institution in Hong Kong with recipients of the Nobel Prize, Turing Award, Fields Medal and Veblen Prize sitting as faculty in residence. CUHK graduates are connected worldwide through an extensive alumni network. CUHK undertakes a wide range of research programmes in many subject areas, and strives to provide scope for all academic staff to undertake consultancy and collaborative projects with industry.

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