AimGel: Supercharing Cell Therapy Production and Development

Overview

Allegrow Biotech innovates biomaterial-based solutions for R&D and production of therapeutic cells. Developing versatile “AimGel”, a cell mimetic microgel platform formulated with synthetic polysaccharides, lipids and recombinant proteins. AimGel platform has wide applications, facilitate R&D and clinical translation of immune cell therapies.

Problem addressed

An artificial cell-based system for ex vivo live cell growth and manipulation in cell therapy.

Innovation

Doubling Efficiency: Cell-mimicking approach enables superior interaction with immune cells, improving T-cell growth 2X faster and 4X more cells than existing materials.
Customizable Flexibility: Customizable signals allow AimGel technology to rapidly cater to different cell types, expanding therapeutic potential.
Seamless Integration: Compatible with existing cell production workflows, minimizing switching cost while maximizing performance

Award

Launching T cell (RUO) product in 2024, other 2 MVPs to be ready
T cell reagent MVP has been validated by 5 cell therapy Biotechs
Awarded TSSSU 2023 & 2024, Gold medal in Geneva inventions exhibition 2023

Application

cell therapy

Project Members

Allegrow Biotech Ltd.

Patent

HK62024091500.4
CN202380012142.7
US18/565591
PCT/IB2023/000557

Website

The Hong Kong University of Science and Technology (HKUST)

The Hong Kong University of Science and Technology (HKUST) (https://hkust.edu.hk/) is a world-class research intensive university that focuses on science, technology and business as well as humanities and social science. HKUST offers an international campus, and a holistic and interdisciplinary pedagogy to nurture well-rounded graduates with global vision, a strong entrepreneurial spirit and innovative thinking. Over 80% of our research work were rated “Internationally excellent” or “world leading” in the Research Assessment Exercise 2020 of Hong Kong’s University Grants Committee. We were ranked 3rd in Times Higher Education’s Young University Rankings 2022, and our graduates were ranked 23rd worldwide and among the best from universities from Asia in Global University Employability Survey 2021.

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