Optic Therapeutics Against age-related macular degeneration (AMD)

HKUST
Overview

Therapeutic identification of resveratrol, polydatin and/or its analogues as an eyedrop treatment against age-related macular degeneration (AMD) by inhibiting VEGF-mediated angiogenesis.

  • Optic Therapeutics Against age-related macular degeneration (AMD) 0
  • Optic Therapeutics Against age-related macular degeneration (AMD) 1
Problem addressed

Development of anti-angiogenic eyedrop for eye disease

Innovation
  • Solid discovery and clinical applications of VEGF-targeted drugs derived from Traditional Chinese Medicines (TCMs) [7 publications and 2 Chinese patents]
  • Phytochemicals targeting VEGF protein with easy administration, low-cost manufacturing, long-term administration and handy ocular instillation
  • Novel treatment and non-invasiveness therapeutic strategy compared with standard clinical options such as argon laser photocoagulation and photodynamic therapies
Application
  • Macular Degeneration Treatment
  • Cancer treatment

Patent

  • CN202211731130.3
The Hong Kong University of Science and Technology (HKUST)

The Hong Kong University of Science and Technology (HKUST) (https://hkust.edu.hk/) is a world-class research intensive university that focuses on science, technology and business as well as humanities and social science. HKUST offers an international campus, and a holistic and interdisciplinary pedagogy to nurture well-rounded graduates with global vision, a strong entrepreneurial spirit and innovative thinking. Over 80% of our research work were rated “Internationally excellent” or “world leading” in the Research Assessment Exercise 2020 of Hong Kong’s University Grants Committee. We were ranked 3rd in Times Higher Education’s Young University Rankings 2022, and our graduates were ranked 23rd worldwide and among the best from universities from Asia in Global University Employability Survey 2021.

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